Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

Nanoparticle (NP) drug delivery systems (5−250 nm) have the potential to improve current disease therapies because of their ability to overcome multiple biological barriers and releasing a therapeutic load in the optimal dosage range. Rapid clearance of circulating nanoparticles during systemic deli...

Full description

Bibliographic Details
Main Authors: Alexis, Frank (Contributor), Molnar, Linda K. (Author), Farokhzad, Omid C. (Contributor), Pridgen, Eric M. (Author)
Other Authors: MIT-Harvard Center for Cancer Nanotechnology Excellence (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Pridgen, Eric (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2012-11-26T19:27:31Z.
Subjects:
Online Access:Get fulltext