Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival

DegP, a member of the highly conserved HtrA family, performs quality-control degradation of misfolded proteins in the periplasm of Gram-negative bacteria and is required for high-temperature survival of Escherichia coli. Substrate binding transforms DegP from an inactive oligomer containing two trim...

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Bibliographic Details
Main Authors: Kim, Seokhee (Contributor), Sauer, Robert T (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Sauer, Robert T. (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences, 2012-12-11T14:50:35Z.
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