Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival
DegP, a member of the highly conserved HtrA family, performs quality-control degradation of misfolded proteins in the periplasm of Gram-negative bacteria and is required for high-temperature survival of Escherichia coli. Substrate binding transforms DegP from an inactive oligomer containing two trim...
Main Authors: | Kim, Seokhee (Contributor), Sauer, Robert T (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Sauer, Robert T. (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences,
2012-12-11T14:50:35Z.
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Subjects: | |
Online Access: | Get fulltext |
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