17(lowercase beta)-estradiol and Tamoxifen prevent gastric cancer by modulating leukocyte recruitment and oncogenic pathways in Helicobacter pylori-infected INS-GAS male mice
Helicobacter pylori infection promotes male predominant gastric adenocarcinoma in humans. Estrogens reduce gastric cancer risk and previous studies showed that prophylactic 17β-estradiol (E2) in INS-GAS mice decreases H. pylori-induced carcinogenesis. We examined the effect of E2 and tamoxifen (TAM)...
Main Authors: | Sheh, Alexander (Contributor), Ge, Zhongming (Contributor), Parry, Nicola Maria Anne (Contributor), Muthupalani, Sureshkumar (Contributor), Rager, Julia E. (Author), Raczynski, Arkadiusz R. (Contributor), Mobley, Melissa W. (Contributor), McCabe, Amanda F. (Contributor), Fry, Rebecca C. (Author), Wang, Timothy C. (Author), Fox, James G. (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Association for Cancer Research,
2012-12-12T18:30:46Z.
|
Subjects: | |
Online Access: | Get fulltext |
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