Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium

Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium

Intestinal epithelial cells exist within a complex environment that affects how they interpret and respond to stimuli. We have applied a multi-scale in vivo systems approach to understand how intestinal immune cells communicate with epithelial cells to regulate responses to inflammatory signals. Mul...

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Bibliographic Details
Main Authors: Cortez-Retamozo, Virna (Author), Philips, Sarah R. (Author), Pittet, Mikael J. (Author), Haigis, Kevin M. (Author), Lau, Ken S. (Author), Lauffenburger, Douglas A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Lau, Ken Siu-Kwong (Contributor), Lauffenburger, Douglas A. (Contributor)
Format: Article
Language:English
Published: PLoS Computational Biology, 2013-01-10T17:56:22Z.
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