Derlin-2-Deficient Mice Reveal an Essential Role for Protein Dislocation in Chondrocytes

Protein quality control is a balance between chaperone-assisted folding and removal of misfolded proteins from the endoplasmic reticulum (ER). Cell-based assays have been used to identify key players of the dislocation machinery, including members of the Derlin family. We generated conditional knock...

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Bibliographic Details
Main Authors: Ploegh, Hidde (Contributor), Kim, Jun (Contributor), Dougan, Stephanie K. (Author), Hu, Chih-Chi Andrew (Author), Paquet, Marie-Eve (Author), Greenblatt, Matthew B. (Author), Lilley, Brendan N. (Author), Watson, Nicki (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: American Society for Microbiology, 2013-01-10T21:50:03Z.
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