The eradication of bacterial persisters with antibiotic-generated hydroxyl radical
During Mycobacterium tuberculosis infection, a population of bacteria likely becomes refractory to antibiotic killing in the absence of genotypic resistance, making treatment challenging. We describe an in vitro model capable of yielding a phenotypically antibiotic-tolerant subpopulation of cells, o...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2013-02-05T18:32:09Z.
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Subjects: | |
Online Access: | Get fulltext |