Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

Unusually effective microRNA targeting within repeat-rich coding regions of mammalian mRNAs

MicroRNAs (miRNAs) regulate numerous biological processes by base-pairing with target messenger RNAs (mRNAs), primarily through sites in 3' untranslated regions (UTRs), to direct the repression of these targets. Although miRNAs have sometimes been observed to target genes through sites in open...

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Bibliographic Details
Main Authors: Schnall-Levin, Michael (Contributor), Rissland, Olivia S. (Contributor), Johnston, Wendy K. (Contributor), Perrimon, Norbert (Author), Bartel, David (Contributor), Berger Leighton, Bonnie (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor), Berger, Bonnie (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2013-02-13T15:51:14Z.
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