Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways

Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways

Modeling of signal transduction pathways plays a major role in understanding cells' function and predicting cellular response. Mathematical formalisms based on a logic formalism are relatively simple but can describe how signals propagate from one protein to the next and have led to the constru...

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Main Authors: Mitsos, Alexander (Contributor), Melas, Ioannis N. (Author), Morris, Melody Kay (Contributor), Saez-Rodriguez, Julio (Author), Lauffenburger, Douglas A. (Contributor), Alexopoulos, Leonidas G. (Author)
Other Authors: Massachusetts Institute of Technology. Cell Decision Process Center (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-02-26T21:55:43Z.
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