Self-folding and aggregation of amyloid nanofibrils

Amyloids are highly organized protein filaments, rich in β-sheet secondary structures that self-assemble to form dense plaques in brain tissues affected by severe neurodegenerative disorders (e.g. Alzheimer's Disease). Identified as natural functional materials in bacteria, in addition to their...

Full description

Bibliographic Details
Main Authors: Paparcone, Raffaella (Contributor), Cranford, Steven Wayne (Contributor), Buehler, Markus J. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Materials Science and Engineering (Contributor), Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor), Massachusetts Institute of Technology. Laboratory for Atomistic and Molecular Mechanics (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, The, 2013-02-28T19:40:49Z.
Subjects:
Online Access:Get fulltext