The impact of negative selection on thymocyte migration in the medulla
Developing thymocytes are screened for self-reactivity before they exit the thymus, but how thymocytes scan the medulla for self antigens is unclear. Using two-photon microscopy, we observed that medullary thymocytes migrated rapidly and made frequent, transient contacts with dendritic cells. In the...
Main Authors: | , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2013-03-21T16:02:33Z.
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Subjects: | |
Online Access: | Get fulltext |