Evolving a robust signal transduction pathway from weak cross-talk
We have evolved a robust two-component signal transduction pathway from a sensor kinase (SK) and non-partner response regulator (RR) that show weak cross-talk in vitro and no detectable cross-talk in vivo in wild-type strains. The SK, CpxA, is bifunctional, with both kinase and phosphatase activitie...
| Main Authors: | , , |
|---|---|
| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2013-03-27T15:14:50Z.
|
| Subjects: | |
| Online Access: | Get fulltext |