High-resolution genetic mapping with pooled sequencing

Background: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. However, the uncertainty from pooling and the challenge of noisy sequencing data de...

Full description

Bibliographic Details
Main Authors: Edwards, Matthew Douglas (Contributor), Gifford, David K. (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2013-05-02T17:39:45Z.
Subjects:
Online Access:Get fulltext