Contrasting Effects of Vasculogenic Induction Upon Biaxial Bioreactor Stimulation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Cocultures in Three-Dimensional Scaffolds under in Vitro and in Vivo Paradigms for Vascularized Bone Tissue Engineering

Contrasting Effects of Vasculogenic Induction Upon Biaxial Bioreactor Stimulation of Mesenchymal Stem Cells and Endothelial Progenitor Cells Cocultures in Three-Dimensional Scaffolds under in Vitro and in Vivo Paradigms for Vascularized Bone Tissue Engineering

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Clinical translation of bone tissue engineering approaches for fracture repair has been hampered by inadequate vascularization required for maintaining cell survival, skeletal regeneration, and remodeling. The potential of vasculature formation within tissue-engineered grafts depends on various fact...

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Bibliographic Details
Main Authors: Liu, Yuchun (Author), Teoh, Swee-Hin (Author), Chong, Mark S. K. (Author), Yeow, Chen-Hua (Author), Kamm, Roger Dale (Contributor), Choolani, Mahesh (Author), Chan, Jerry K. Y. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Singapore-MIT Alliance in Research and Technology (SMART) (Contributor)
Format: Article
Language:English
Published: Mary Ann Liebert, Inc., 2013-05-07T18:25:33Z.
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