Photoswitchable Nanoparticles for Triggered Tissue Penetration and Drug Delivery

Photoswitchable Nanoparticles for Triggered Tissue Penetration and Drug Delivery

We report a novel nanoparticulate drug delivery system that undergoes reversible volume change from 150 to 40 nm upon phototriggering with UV light. The volume change of these monodisperse nanoparticles comprising spiropyran, which undergoes reversible photoisomerization, and PEGylated lipid enables...

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Bibliographic Details
Main Authors: Tong, Rong (Contributor), Hemmati, Houman D. (Author), Kohane, Daniel S. (Author), Langer, Robert S (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Langer, Robert (Contributor)
Format: Article
Language:English
Published: 2013-06-13T20:12:53Z.
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