Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?

Abstract Background: Fragile X syndrome (FXS) is a common inherited form of intellectual disability caused by loss of function of the fragile X mental retardation protein. Recent animal studies suggest that upregulated downstream signaling by metabotropic glutamate receptor 5 (mGluR5) might be an im...

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Bibliographic Details
Main Authors: Lohith, Talakad G. (Author), Osterweil, Emily (Contributor), Fujita, Masahiro (Author), Jenko, Kimberly J. (Author), Bear, Mark (Contributor), Innis, Robert B. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd, 2013-06-17T13:10:29Z.
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