Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

The siRNA transfection efficiency of nanoparticles (NPs), composed of a superparamagnetic iron oxide core modified with polycationic polymers (poly(hexamethylene biguanide) or branched polyethyleneimine), were studied in CHO-K1 and HeLa cell lines. Both NPs demonstrated to be good siRNA transfection...

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Bibliographic Details
Main Authors: Castillo, Betzaida (Author), Badillo, Valerie (Author), Hatton, T. Alan (Contributor), Barletta, Gabriel (Author), Bromberg, Lev E. (Contributor), Lopez, Xaira (Author), Gonzalez Feliciano, Jose A. (Author), Gonzalez, Carlos I. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: Hindawi Publishing Corporation, 2013-06-17T13:32:33Z.
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