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79375 |
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|a dc
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|a DeMuth, Peter Charles
|e author
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|a Massachusetts Institute of Technology. Institute for Soldier Nanotechnologies
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|a Massachusetts Institute of Technology. Department of Biological Engineering
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|a Massachusetts Institute of Technology. Department of Chemical Engineering
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|a Massachusetts Institute of Technology. Department of Materials Science and Engineering
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|a Ragon Institute of MGH, MIT and Harvard
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|a Koch Institute for Integrative Cancer Research at MIT
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|a DeMuth, Peter Charles
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|a Su, Xingfang
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|a Samuel, Raymond E.
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|a Hammond, Paula T.
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|a Irvine, Darrell J.
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|a Su, Xingfang
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|a Samuel, Raymond E.
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|a Hammond, Paula T
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|a Irvine, Darrell J
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|a Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA
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|b Wiley-Blackwell Publishers,
|c 2013-06-26T16:33:34Z.
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|z Get fulltext
|u http://hdl.handle.net/1721.1/79375
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|a Multilayer-coated microneedles achieve transcutaneous delivery of plasmid DNA to the viable epidermis. Cy3-labeled plasmid DNA encoding luciferase (yellow) is deposited on biodegradable microneedle arrays through multilayer self-assembly and then delivered to the skin by microneedle application to achieve colocalization with Langerhans dendritic cells (MHC II-GFP-green).
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|a United States. Dept. of Defense (DAAD19- 02-D-0002)
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|a United States. Dept. of Defense (W911NF-07-D-0004)
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|a Ragon Institute of MGH, MIT and Harvard
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|a National Institutes of Health (U.S.) (NIH Biotechnology Training Program at MIT)
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|a Howard Hughes Medical Institute (Investigator)
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|a en_US
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|a Article
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|t Advanced Materials
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