Hepatic Stellate Cell-Targeted Delivery of Hepatocyte Growth Factor Transgene via Bile Duct Infusion Enhances Its Expression at Fibrotic Foci to Regress Dimethylnitrosamine-Induced Liver Fibrosis
Liver fibrosis generates fibrotic foci with abundant activated hepatic stellate cells and excessive collagen deposition juxtaposed with healthy regions. Targeted delivery of antifibrotic therapeutics to hepatic stellate cells (HSCs) might improve treatment outcomes and reduce adverse effects on heal...
Main Authors: | , , , , , , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Mary Ann Liebert,
2013-09-11T16:31:32Z.
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Subjects: | |
Online Access: | Get fulltext |