Rapid, modular and reliable construction of complex mammalian gene circuits

Rapid, modular and reliable construction of complex mammalian gene circuits

We developed a framework for quick and reliable construction of complex gene circuits for genetically engineering mammalian cells. Our hierarchical framework is based on a novel nucleotide addressing system for defining the position of each part in an overall circuit. With this framework, we demonst...

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Bibliographic Details
Main Authors: Guye, Patrick (Contributor), Li, Yinqing (Contributor), Wroblewska, Liliana (Contributor), Duportet, Xavier (Contributor), Weiss, Ron (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2013-09-13T15:04:09Z.
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