Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

In metazoans, the nuclear lamina is thought to play an important role in the spatial organization of interphase chromosomes, by providing anchoring sites for large genomic segments named lamina-associated domains (LADs). Some of these LADs are cell-type specific, while many others appear constitutiv...

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Main Authors: Meuleman, Wouter (Contributor), Peric-Hupkes, Daan (Author), Kind, Jop (Author), Beaudry, Jean-Bernard (Author), Pagie, Ludo (Author), Kellis, Manolis (Contributor), Reinders, Marcel (Author), Wessels, Lodewyk (Author), van Steensel, Bas (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2013-09-18T14:34:27Z.
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