The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells

In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. This transition is associated with silencing of the pluripotency genes Oct4 and Nanog. Interestingly, these genes are repressed at different develop...

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Bibliographic Details
Main Authors: Okumura, Leah M. (Contributor), Lesch, Bluma J. (Author), Page, David C. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Lesch, Bluma (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-09-26T19:51:17Z.
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