DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis

DNA methylation regulates gene expression in many organisms. In eukaryotes, DNA methylation is associated with gene repression, while it exerts both activating and repressive effects in the Proteobacteria through largely locus-specific mechanisms. Here, we identify a critical DNA methyltransferase i...

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Bibliographic Details
Main Authors: Shell, Scarlet S. (Author), Baek, Seung-Hun (Author), Shah, Rupal R. (Author), Sassetti, Christopher M. (Author), Dedon, Peter C. (Contributor), Fortune, Sarah M. (Author), Prestwich, Erin (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-09-30T14:57:48Z.
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