DNA Methylation Impacts Gene Expression and Ensures Hypoxic Survival of Mycobacterium tuberculosis
DNA methylation regulates gene expression in many organisms. In eukaryotes, DNA methylation is associated with gene repression, while it exerts both activating and repressive effects in the Proteobacteria through largely locus-specific mechanisms. Here, we identify a critical DNA methyltransferase i...
Main Authors: | Shell, Scarlet S. (Author), Baek, Seung-Hun (Author), Shah, Rupal R. (Author), Sassetti, Christopher M. (Author), Dedon, Peter C. (Contributor), Fortune, Sarah M. (Author), Prestwich, Erin (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2013-09-30T14:57:48Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis.
by: Scarlet S Shell, et al.
Published: (2013-01-01) -
The enduring hypoxic response of Mycobacterium tuberculosis.
by: Tige R Rustad, et al.
Published: (2008-01-01) -
Citrate lyase CitE in Mycobacterium tuberculosis contributes to mycobacterial survival under hypoxic conditions.
by: Jialing Hu, et al.
Published: (2020-01-01) -
Defining the Transcriptional and Post-transcriptional Landscapes of Mycobacterium smegmatis in Aerobic Growth and Hypoxia
by: M. Carla Martini, et al.
Published: (2019-03-01) -
Tolerating the Unwelcome Guest; How the Host Withstands Persistent Mycobacterium tuberculosis
by: Andrew J. Olive, et al.
Published: (2018-09-01)