H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation

H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation

The histone H2A variant H2A.Z is essential for embryonic development and for proper control of developmental gene expression programs in embryonic stem cells (ESCs). Divergent regions of amino acid sequence of H2A.Z likely determine its functional specialization compared to core histone H2A. For exa...

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Main Authors: Subramanian, Vidya (Contributor), Mazumder, Aprotim (Contributor), Fields, Paul A. (Contributor), Torrey, Lillian (Contributor), Levine, Stuart S. (Contributor), Bathe, Mark (Contributor), Surface, Lauren Elizabeth (Contributor), Alwan, Allison M. (Contributor), Thai, Kevin Kinh (Contributor), Boyer, Laurie Ann (Author), Butty, Vincent L G (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Laboratory for Computational Cell Biology & Biophysics (Contributor), Boyer, Laurie (Contributor), Butty, Vincent (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2013-09-30T15:28:10Z.
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