Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

An effective response to DNA damaging agents involves modulating numerous facets of cellular homeostasis in addition to DNA repair and cell-cycle checkpoint pathways. Fluorescence microscopy-based imaging offers the opportunity to simultaneously interrogate changes in both protein level and subcellu...

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Main Authors: Mazumder, Aprotim (Contributor), Bathe, Mark (Contributor), Samson, Leona D. (Contributor), Pesudo Quiros, Laia (Contributor), McRee, Siobhan K. (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Laboratory for Computational Cell Biology & Biophysics (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2013-10-07T14:42:54Z.
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