An Efficient Process for Pd-Catalyzed C−N Cross-Coupling Reactions of Aryl Iodides: Insight Into Controlling Factors

An investigation into Pd-catalyzed C−N cross-coupling reactions of aryl iodides is described. NaI is shown to have a significant inhibitory effect on these processes. By switching to a solvent system in which the iodide byproduct was insoluble, reactions of aryl iodides were accomplished with the sa...

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Bibliographic Details
Main Authors: Fors, Brett P. (Contributor), Buchwald, Stephen Leffler (Contributor), Davis, Nicole Rose (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2013-11-13T15:56:34Z.
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