Mechanism-Based Triarylphosphine-Ester Probes for Capture of Endogenous RSNOs

Nitrosothiols (RSNOs) have been proposed as important intermediates in nitric oxide (NO[superscript •]) metabolism, storage, and transport as well as mediators in numerous NO-signaling pathways. RSNO levels are finely regulated, and dysregulation is associated with the etiology of several pathologie...

Full description

Bibliographic Details
Main Authors: Wishnok, John S. (Contributor), Wogan, Gerald N. (Contributor), Seneviratne, Uthpala I. (Contributor), Godoy, Luiz Claudio (Contributor), Tannenbaum, Steven Robert (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2013-11-13T16:59:08Z.
Subjects:
Online Access:Get fulltext