Water Overcomes Methyl Group Directing Effects in Epoxide-Opening Cascades
Water is an effective promoter of the endo-selective opening of trisubstituted epoxides, enabling related cascades leading to a variety of substituted ladder polyether structures. When used in conjunction with a tetrahydropyran-templated nucleophile, water can overcome the powerful electronic direct...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2013-11-15T15:12:16Z.
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| Subjects: | |
| Online Access: | Get fulltext |