Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting
The five platinum anticancer compounds currently in clinical use conform to structure-activity relationships formulated (M. J. Cleare and J. D. Hoeschele, Bioinorg. Chem., 1973, 2, 187-210) shortly after the discovery that cis-diamminedichloroplatinum(II), cisplatin, has antitumor activity in mice....
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| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry, The,
2013-11-15T19:58:47Z.
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| Online Access: | Get fulltext |