Structure of yeast Argonaute with guide RNA

Structure of yeast Argonaute with guide RNA

The RNA-induced silencing complex, comprising Argonaute and guide RNA, mediates RNA interference. Here we report the 3.2 Å crystal structure of Kluyveromyces polysporus Argonaute (KpAGO) fortuitously complexed with guide RNA originating from small-RNA duplexes autonomously loaded and processed by r...

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Main Authors: Nakanishi, Kotaro (Author), Weinberg, David E. (Contributor), Bartel, David (Contributor), Patel, Dinshaw J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2013-12-19T19:43:50Z.
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