X-ray structure of an AdoMet radical activase reveals an anaerobic solution for formylglycine posttranslational modification

Arylsulfatases require a maturating enzyme to perform a co- or posttranslational modification to form a catalytically essential formylglycine (FGly) residue. In organisms that live aerobically, molecular oxygen is used enzymatically to oxidize cysteine to FGly. Under anaerobic conditions, S-adenosyl...

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Bibliographic Details
Main Authors: Goldman, Peter J. (Contributor), McLaughlin, Martin I. (Contributor), Drennan, Catherine L. (Contributor), Grove, Tyler L. (Author), Sites, Lauren A. (Author), Booker, Squire J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2013-12-30T18:11:37Z.
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