The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

The inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics

Phosphatidylinositol (PI) 4,5-bisphosphate (PI(4,5)P[subscript 2]) and its phosphorylated product PI 3,4,5-triphosphate (PI(3,4,5)P[subscript 3]) are two major phosphoinositides concentrated at the plasma membrane. Their levels, which are tightly controlled by kinases, phospholipases, and phosphatas...

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Main Authors: Gertler, Frank (Contributor), Nakatsu, Fubito (Author), Perera, Rushika M. (Author), Lucast, Louise (Author), Zoncu, Roberto (Author), Domin, Jan (Author), Toomre, Derek (Author), De Camilli, Pietro (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, 2014-01-06T15:25:29Z.
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