Statistical Experimental Design Guided Optimization of a One-Pot Biphasic Multienzyme Total Synthesis of Amorpha-4,11-diene
In vitro synthesis of chemicals and pharmaceuticals using enzymes is of considerable interest as these biocatalysts facilitate a wide variety of reactions under mild conditions with excellent regio-, chemo- and stereoselectivities. A significant challenge in a multi-enzymatic reaction is the need to...
Main Authors: | , , , , , |
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Other Authors: | , |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2014-01-06T19:38:15Z.
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Subjects: | |
Online Access: | Get fulltext |