Sirtuin deacetylases in neurodegenerative diseases of aging
Sirtuin enzymes are a family of highly conserved protein deacetylases that depend on nicotinamide adenine dinucleotide (NAD+) for their activity. There are seven sirtuins in mammals and these proteins have been linked with caloric restriction and aging by modulating energy metabolism, genomic stabil...
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2014-01-24T17:17:02Z.
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| Subjects: | |
| Online Access: | Get fulltext |