Evolving a robust signal transduction pathway from weak cross-talk
We have evolved a robust two‐component signal transduction pathway from a sensor kinase (SK) and non‐partner response regulator (RR) that show weak cross‐talk in vitro and no detectable cross‐talk in vivo in wild‐type strains. The SK, CpxA, is bifunctional, with both kinase and phosphatase activitie...
| Main Authors: | , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2014-02-07T14:34:09Z.
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| Subjects: | |
| Online Access: | Get fulltext |