Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules

Arboretum: Reconstruction and analysis of the evolutionary history of condition-specific transcriptional modules

Comparative functional genomics studies the evolution of biological processes by analyzing functional data, such as gene expression profiles, across species. A major challenge is to compare profiles collected in a complex phylogeny. Here, we present Arboretum, a novel scalable computational algorith...

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Main Authors: Kellis, Manolis (Contributor), Regev, Aviv (Contributor), Roy, Sushmita (Author), Wapinski, Ilan (Author), Pfiffner, Jenna (Author), French, Courtney (Author), Socha, Amanda (Author), Konieczka, Jay (Author), Habib, Naomi (Author), Thompson, Dawn (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2014-02-14T16:59:33Z.
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