Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles

Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles

The construction of nanostructures from biodegradable precursors and shell/core crosslinking have been pursued as strategies to solve the problems of toxicity and limited stability, respectively. Polyphosphoester (PPE)-based micelles and crosslinked nanoparticles with non-ionic, anionic, cationic, a...

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Bibliographic Details
Main Authors: Elsabahy, Mahmoud (Author), Zhang, Shiyi (Contributor), Zhang, Fuwu (Author), Deng, Zhou J. (Contributor), Lim, Young H. (Author), Parsamian, Perouza (Author), Wooley, Karen L. (Author), Wang, Hai, Ph. D. Massachusetts Institute of Technology (Author), Hammond, Paula T (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hammond, Paula T. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-02-19T15:36:47Z.
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