Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells

Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells

Diabetes is caused by the loss or dysfunction of insulin-secreting β-cells in the pancreas. β-cells reduce their mass and lose insulin-producing ability in vitro, likely due to insufficient cell-cell and cell-extracellular matrix (ECM) interactions as β-cells lose their native microenvironment. Here...

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Bibliographic Details
Main Authors: Lee, Samuel (Author), Ma, Minglin (Contributor), Kim, Soo Min (Author), Guye, Patrick (Contributor), Pancoast, James R. (Author), Weiss, Ron (Contributor), Lee, Richard T. (Author), Anderson, Daniel Griffith (Contributor), Hammond, Paula T (Author), Li, W. (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Li, Wei (Contributor), Hammond, Paula T. (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-02-19T17:30:39Z.
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