Identifying Recent Adaptations in Large-Scale Genomic Data

Identifying Recent Adaptations in Large-Scale Genomic Data

Although several hundred regions of the human genome harbor signals of positive natural selection, few of the relevant adaptive traits and variants have been elucidated. Using full-genome sequence variation from the 1000 Genomes (1000G) Project and the composite of multiple signals (CMS) test, we in...

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Main Authors: Andersen, Kristian G. (Author), Tabrizi, Shervin (Author), Winnicki, Sarah (Author), Yen, Angela (Contributor), Park, Daniel J (Author), Griesemer, Dustin (Author), Karlsson, Elinor K. (Author), Wong, Sunny H (Author), Cabili, Moran N. (Author), Adegbola, Richard A (Author), Bamezai, Rameshwar N.K (Author), Hill, Adrian V. S. (Author), Vannberg, Fredrik O (Author), Rinn, John L. (Author), Schaffner, Stephen F (Author), Sabeti, Pardis C (Author), Grossman, Sharon Rachel (Contributor), Shlyakhter, Ilya 1975- (Author), Lander, Eric Steven (Author)
Other Authors: Whitaker College of Health Sciences and Technology (Contributor), Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Lander, Eric S. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2014-03-10T15:06:08Z.
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