Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma

Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma

Metastasis accounts for the vast majority of cancer-related deaths, yet the molecular mechanisms that drive metastatic spread remain poorly understood. Here we report that Tks5, which has been linked to the formation of proteolytic cellular protrusions known as invadopodia, undergoes an isoform swit...

Full description

Bibliographic Details
Main Authors: Chen, Guoan (Author), Dayton, Talya Lucia (Contributor), Kim-Kiselak, Caroline (Contributor), Hoersch, Sebastian (Contributor), Whittaker, Charles A. (Contributor), Bronson, Roderick T. (Author), Beer, David G. (Author), Winslow, Monte M. (Author), Li, Carman Man-Chung (Author), Jacks, Tyler E (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Li, Carman Man Chung (Contributor), Jacks, Tyler E. (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2014-03-14T15:03:40Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items