Quantifying Missing Heritability at Known GWAS Loci

Quantifying Missing Heritability at Known GWAS Loci

Recent work has shown that much of the missing heritability of complex traits can be resolved by estimates of heritability explained by all genotyped SNPs. However, it is currently unknown how much heritability is missing due to poor tagging or additional causal variants at known GWAS loci. Here, we...

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Main Authors: Gusev, Alexander (Author), Bhatia, Gaurav (Contributor), Zaitlen, Noah (Author), Vilhjalmsson, Bjarni J. (Author), Diogo, Dorothee (Author), Stahl, Eli A. (Author), Gregersen, Peter K. (Author), Worthington, Jane (Author), Klareskog, Lars (Author), Raychaudhuri, Soumya (Author), Plenge, Robert M. (Author), Pasaniuc, Bogdan (Author), Price, Alkes L. (Author)
Other Authors: Whitaker College of Health Sciences and Technology (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-04-04T13:45:14Z.
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