Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

Identification of apolipoprotein D as a cardioprotective gene using a mouse model of lethal atherosclerotic coronary artery disease

Mice with homozygous null mutations in the HDL receptor (scavenger receptor class B, type I, or SR-BI) and apolipoprotein E (apoE) genes [SR-BI/apoE double KO (SR-BI[superscript −/−]/apoE[superscript −/−] or dKO) mice] spontaneously develop occlusive, atherosclerotic coronary artery disease (CAD) an...

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Bibliographic Details
Main Authors: Mani, D. R. (Author), Tsukamoto, Kosuke (Contributor), Zhang, Songwen (Contributor), Krieger, Monty (Contributor), Shi, Jianru (Author), Haagensen, Darrow E. (Author), Otsuka, Fumiyuki (Author), Guan, Jian (Author), Smith, Jonathan D. (Author), Weng, Wei (Author), Liao, Ronglih (Author), Kolodgie, Frank D. (Author), Virmani, Renu (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2014-04-07T17:28:08Z.
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