Regulatory T Cells Expanded from Hiv-1-Infected Individuals Maintain Phenotype, Tcr Repertoire and Suppressive Capacity

Regulatory T Cells Expanded from Hiv-1-Infected Individuals Maintain Phenotype, Tcr Repertoire and Suppressive Capacity

While modulation of regulatory T cell (Treg) function and adoptive Treg transfer are being explored as therapeutic modalities in the context of autoimmune diseases, transplantation and cancer, their role in HIV-1 pathogenesis remains less well defined. Controversy persists regarding their beneficial...

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Main Authors: Angin, Mathieu (Author), Klarenbeek, Paul L. (Author), King, Melanie (Author), Sharma, Siddhartha M. (Author), Moodley, Eshia S. (Author), Rezai, Ashley (Author), Piechocka-Trocha, Alicja (Author), Toth, Ildiko (Author), Chan, Andrew T. (Author), Goulder, Philip J. R. (Author), Ndung'u, Thumbi (Author), Kwon, Douglas (Contributor), Addo, Marylyn M. (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-04-15T20:19:59Z.
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