Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

Toxoplasma gondii is an intracellular parasite that infects a wide range of warm-blooded species. Rats vary in their susceptibility to this parasite. The Toxo1 locus conferring Toxoplasma resistance in rats was previously mapped to a region of chromosome 10 containing Nlrp1. This gene encodes an inf...

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Bibliographic Details
Main Authors: Cirelli, Kimberly (Contributor), Gorfu, Gezahegn (Author), Hassan, Musa A. (Contributor), Printz, Morton (Author), Crown, Devorah (Author), Leppla, Stephen H. (Author), Grigg, Michael E. (Author), Saeij, Jeroen (Contributor), Moayeri, Mahtab (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2014-04-30T21:00:44Z.
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