High Avidity CD8+ T Cells Efficiently Eliminate Motile HIV-Infected Targets and Execute a Locally Focused Program of Anti-Viral Function
The dissemination of HIV from an initial site of infection is facilitated by motile HIV-infected CD4+ T-cells. However, the impact of infected target cell migration on antigen recognition by HIV-specific CD8+ T-cells is unclear. Using a 3D in vitro model of tissue, we visualized dynamic interactions...
Main Authors: | , , , , , , , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
Public Library of Science,
2014-05-02T16:56:39Z.
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Subjects: | |
Online Access: | Get fulltext |