Three Periods of Regulatory Innovation During Vertebrate Evolution

Three Periods of Regulatory Innovation During Vertebrate Evolution

The gain, loss, and modification of gene regulatory elements may underlie a substantial proportion of phenotypic changes on animal lineages. To investigate the gain of regulatory elements throughout vertebrate evolution, we identified genome-wide sets of putative regulatory regions for five vertebra...

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Main Authors: Kellis, Manolis (Contributor), Lowe, Craig B. (Author), Siepel, Adam (Author), Raney, Brian J. (Author), Clamp, Michele (Author), Salama, Sofie R. (Author), Kingsley, David M. (Author), Lindblad-Toh, Kerstin (Author), Haussler, David (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2014-05-15T19:40:28Z.
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