Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

Transcription of long noncoding RNAs (lncRNAs) within gene regulatory elements can modulate gene activity in response to external stimuli, but the scope and functions of such activity are not known. Here we use an ultrahigh-density array that tiles the promoters of 56 cell-cycle genes to interrogate...

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Main Authors: Hung, Tiffany (Author), Wang, Yulei (Author), Lin, Michael F. (Contributor), Koegel, Ashley K. (Author), Kotake, Yojiro (Author), Grant, Gavin D. (Author), Horlings, Hugo M. (Author), Shah, Nilay (Author), Umbricht, Christopher (Author), Wang, Pei (Author), Wang, Yu (Author), Kong, Benjamin (Author), Langerød, Anita (Author), Børresen-Dale (Author), Kim, Seung K. (Author), van de Vijver, Marc (Author), Sukumar, Saraswati (Author), Whitfield, Michael L. (Author), Kellis, Manolis (Contributor), Xiong, Yue (Author), Wong, David J. (Author), Chang, Howard Y. (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2014-05-16T16:50:27Z.
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