Noncanonical Role of the PDZ4 Domain of the Adaptor Protein PDZK1 in the Regulation of the Hepatic High Density Lipoprotein Receptor Scavenger Receptor Class B, Type I (SR-BI)

Noncanonical Role of the PDZ4 Domain of the Adaptor Protein PDZK1 in the Regulation of the Hepatic High Density Lipoprotein Receptor Scavenger Receptor Class B, Type I (SR-BI)

The four PDZ (PDZ1 to PDZ4) domain-containing adaptor protein PDZK1 controls the expression, localization, and function of the HDL receptor scavenger receptor class B, type I (SR-BI), in hepatocytes in vivo. This control depends on both the PDZ4 domain and the binding of SR-BI's cytoplasmic C t...

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Main Authors: Tsukamoto, Kosuke (Contributor), Wales, Thomas E. (Author), Daniels, Kathleen (Author), Pal, Rinku (Author), Sheng, Ren (Author), Cho, Wonhwa (Author), Stafford, Walter (Author), Engen, John R. (Author), Krieger, Monty (Contributor), Kocher, Olivier (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: American Society for Biochemistry and Molecular Biology (ASBMB), 2014-06-11T15:08:31Z.
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