An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge

Background: There is tremendous potential for genome sequencing to improve clinical diagnosis and care once it becomes routinely accessible, but this will require formalizing research methods into clinical best practices in the areas of sequence data generation, analysis, interpretation and reportin...

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Main Authors: Brownstein, Catherine A. (Author), Beggs, Alan H. (Author), Homer, Nils (Author), Merriman, Barry (Author), Yu, Timothy W. (Author), Flannery, Katherine C. (Author), DeChene, Elizabeth T. (Author), Towne, Meghan C. (Author), Savage, Sarah K. (Author), Price, Emily N. (Author), Holm, Ingrid A. (Author), Luquette, Lovelace J. (Author), Lyon, Elaine (Author), Majzoub, Joseph (Author), Neupert, Peter (Author), McCallie Jr., David (Author), Szolovits, Peter (Contributor), Willard, Huntington F. (Author), Mendelsohn, Nancy J. (Author), Temme, Renee (Author), Finkel, Richard S. (Author), Yum, Sabrina W. (Author), Medne, Livija (Author), Sunyaev, Shamil R. (Author), Adzhubey, Ivan (Author), Cassa, Christopher A. (Author), de Bakker, Paul I. W. (Author), Duzkale, Hatice (Author), Dworzyński, Piotr (Author), Fairbrother, William G. (Author), Francioli, Laurent (Author), Funke, Birgit H. (Author), Giovanni, Monica A. (Author), Handsaker, Robert E. (Author), Lage, Kasper (Author), Lebo, Matthew S. (Author), Lek, Monkol (Author), Leshchiner, Ignaty (Author), MacArthur, Daniel G. (Author), McLaughlin, Heather M. (Author), Murray, Michael F. (Author), Pers, Tune H. (Author), Polak, Paz P. (Author), Raychaudhuri, Soumya (Author), Rehm, Heidi L. (Author), Soemedi, Rachel (Author), Stitziel, Nathan O. (Author), Vestecka, Sara (Author), Supper, Jochen (Author), Gugenmus, Claudia (Author), Klocke, Bernward (Author), Hahn, Alexander (Author), Schubach, Max (Author), Menzel, Mortiz (Author), Biskup, Saskia (Author), Freisinger, Peter (Author), Deng, Mario (Author), Braun, Martin (Author), Perner, Sven (Author), Smith, Richard J. H. (Author), Andorf, Janeen L. (Author), Huang, Jian (Author), Ryckman, Kelli (Author), Sheffield, Val C. (Author), Stone, Edwin M. (Author), Bair, Thomas (Author), Black-Ziegelbein, E. A. (Author), Braun, Terry A. (Author), Darbro, Benjamin (Author), DeLuca, Adam P. (Author), Kolbe, Diana L. (Author), Scheetz, Todd E. (Author), Shearer, Aiden E. (Author), Sompallae, Rama (Author), Wang, Kai (Author), Bassuk, Alexander G. (Author), Edens, Erik (Author), Mathews, Katherine (Author), Moore, Steven A. (Author), Shchelochkov, Oleg A. (Author), Trapane, Pamela (Author), Bossler, Aaron (Author), Campbell, Colleen A. (Author), Heusel, Jonathan W. (Author), Kwitek, Anne (Author), Maga, Tara (Author), Panzer, Karin (Author), Wassink, Thomas (Author), Van Daele, Douglas (Author), Azaiez, Hela (Author), Booth, Kevin (Author), Meyer, Nic (Author), Segal, Michael M. (Author), Williams, Marc S. (Author), Tromp, Gerard (Author), White, Peter (Author), Corsmeier, Donald (Author), Fitzgerald-Butt, Sara (Author), Herman, Gail (Author), Lamb-Thrush, Devon (Author), McBride, Kim L. (Author), Newsom, David (Author), Pierson, Christopher R. (Author), Rakowsky, Alexander T. (Author), Maver, Ales (Author), Lovrečić, Luca (Author), Palandacic, Anja (Author), Peterlin, Borut (Author), Torkamani, Ali (Author), Wedell, Anna (Author), Huss, Mikael (Author), Alexeyenko, Andrey (Author), Lindvall, Jessica M. (Author), Magnusson, Mans (Author), Nilsson, Daniel (Author), Stranneheim, Henrik (Author), Taylan, Fulya (Author), Gilissen, Christian (Author), Hoischen, Alexander (Author), van Bon, Bregje (Author), Yntema, Helger (Author), Nelen, Marcel (Author), Zhang, Weidong (Author), Sager, Jason (Author), Zhang, Lu (Author), Blair, Kathryn (Author), Kural, Deniz (Author), Cariaso, Michael (Author), Lennon, Greg G. (Author), Javed, Asif (Author), Agrawal, Saloni (Author), Ng, Pauline C. (Author), Sandhu, Komal S. (Author), Krishna, Shuba (Author), Veeramachaneni, Vamsi (Author), Isakov, Ofer (Author), Halperin, Eran (Author), Friedman, Eitan (Author), Shomron, Noam (Author), Glusman, Gustavo (Author), Roach, Jared C. (Author), Caballero, Juan (Author), Cox, Hannah C. (Author), Mauldin, Denise (Author), Ament, Seth A. (Author), Rowen, Lee (Author), Richards, Daniel R. (Author), Lucas, F Anthony S. (Author), Gonzalez-Garay, Manuel L. (Author), Caskey, C. T. (Author), Bai, Yu (Author), Huang, Ying (Author), Fang, Fang (Author), Zhang, Yan (Author), Wang, Zhengyuan (Author), Barrera, Jorge (Author), Garcia-Lobo, Juan M. (Author), González-Lamuno, Domingo (Author), Llorca, Javier (Author), Rodriguez, Maria C. (Author), Varela, Ignacio (Author), Reese, Martin G. (Author), De La Vega, Francisco M. (Author), Kiruluta, Edward (Author), Cargill, Michele (Author), Hart, Reece K. (Author), Sorenson, Jon M. (Author), Lyon, Gholson J. (Author), Stevenson, David A. (Author), Bray, Bruce E. (Author), Moore, Barry M. (Author), Eilbeck, Karen (Author), Yandell, Mark (Author), Zhao, Hongyu (Author), Hou, Lin (Author), Chen, Xiaowei (Author), Yan, Xiting (Author), Chen, Mengjie (Author), Li, Cong (Author), Yang, Can (Author), Gunel, Murat (Author), Li, Peining (Author), Kong, Yong (Author), Alexander, Austin C. (Author), Albertyn, Zayed I. (Author), Boycott, Kym M. (Author), Bulman, Dennis E. (Author), Gordon, Paul M. K. (Author), Innes, A. M. (Author), Knoppers, Bartha M. (Author), Majewski, Jacek (Author), Marshall, Christian R. (Author), Parboosingh, Jillian S. (Author), Sawyer, Sarah L. (Author), Samuels, Mark E. (Author), Schwartzentruber, Jeremy (Author), Kohane, Isaac (Author), Margulies, David M. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor)
Format: Article
Language:English
Published: BioMed Central Ltd., 2014-06-17T16:37:47Z.
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